Well, since everyone's gathering around the wishing well, I'll toss my two cents into the fountain.
Really, as long as I can fairly consistently craft t2-4 long before looting those same quality items, I'll feel as though my choice to specialize in certain weapons is paying off, and I'm getting full perk value from spending those points.
As long as my highest craftable tier gears me up well enough to tackle the high end dungeons (Oh, wait, sorry, PoI's) that will probably give me the quality pinnacles, I'm good with that, too.
My desire between crafting and looting, is to be able to use crafting to outfit myself in my chosen specializations, so that I can in turn knock enough teeth around (still mainlining fortitude and loving it) to get my "dungeon drops". Sure, we're not there yet, but as a thousand dead horses can tell you:
It's Experimental.