Using more than four cores did not hurt me a bit. It helped, but VERY little. If I disable HT on my i7-6950X and set affinity to four cores only, I get around 100-144fps depending on where in Navezgane I am. If I stand still in one place and enable the other six cores, I gain 6-10fps. Not worth anything unless I was REALLY low on framerate, like sub-30fps. I play in 2560x1440, true/native 2K. Now, when I take it down to three cores, I drop to 50-60fps. Two cores gives 29-36fps. One is in the teens. What this tells me is that more cores do indeed help, so long as they are real cores and NOT secondary threads.
I just leave HT on normally and play with all 20 logical CPUs and still get 100-144fps. I believe the PCI-E bus gets saturated at times though, hence the drop. I also normally just leave my desktop on the standard 60Hz refresh rate and thus Unity selects 60Hz since it is less capable than the original Quake, so I get a solid 60fps the entire time I play.