I guess you would have to explain exactly HOW a SP character would be screwed if she couldn’t max out all perks. Currently, I don’t believe your premise so let’s start there.
My view is that any player can survive, mine, farm, scavenge, build, defend, trade, craft, battle, explore, swim, drive, etc. with both some strengths and some weaknesses. You tell me what part of the game a single player is locked out of if she can’t get 100% strengths in everything?
Don’t just say there’s screwage. Show me the screwage.