Beelzybub
Tester
That's within the design specs of your cpu. It should do 4600 in turboboost. Turning it off though is a good test for heat and throttling.the CPU clock was at 4500
If things don't improve with it off though, I'd turn it back on.
Since your overnight memory tests didn't find an error, this test is probably a waste of time.I will try running with one stick of 16 gb ram instead of two.
What about the extra power cable to the motherboard? (not the 24 pin) There's an additional 4 or 8 pin connector to your motherboard that needs to be connected. It's normally close to the cpu as it supplies extra current for your processor.I took my computer apart and changed the power cable to the GPU.
You've eliminated a lot of things with your testing so that's good progress.
So far it's not: EAC, Memory, disk corruption, Windows file system corruption, Game file corruption, graphics driver, Antivirus, Mods, ....
How about Heat? You can install an app like HWINFO and track temperatures of your GPU and CPU while the game is running.
If the game doesn't run long enough for you to do that you could check it while running Furmark (for GPU) and Prime95 (for CPU).
These apps stress test your GPU and CPU so are good at finding issues in hardware.