A blood draw kit would be interesting. Blood bags are hard to find, although you can also get them from IV drip stands. But if you could craft them, it would change a lot though only in the late game. For example, the Physician perk at level 3 (Surgeon) could be reduced so bandages wouldn’t be too OP. In the late game, you’d probably choose first aid kits to make them useful at all. Requiring honey to craft a first aid kit would make the crafting meaningful, so it’s not too easy, and the crafting process would be fairly challenging.First Aid Kits requiring honey would still not be the limiting factor in my experience, it would be blood bags, like it is now.
Bring back the blood draw kit!