If there is a Land Claim Block or a Bedroll in the location, the reset script checks for that and will not do anything. It should be noted though that LCB's have been buggy, and will randomly go inactive. An inactive LCB will not prevent the reset.
In short, don't make your home in a POI. In a18 there will be more POI's that don't have quests you can possibly build in for a starter base. POI's were never intended to be used as bases long term that I am aware of.