Run and Gun + Rule 1 + Automatic Weapons + SMG = serious kite mode. Add in Parkour, and you become an absolute maneuver freak with a gun that restores stam, capable of vaulting cars, low walls, and dropping off buildings without becoming a dead cripple. (12 points to start)
That's a hell of a power combo, along with a high fort tank build (healing factor, pain tolerance, Immunity, flurry), you can really do quite a bit of damage.
That's not to be confused with the Tomb Raider combo (Lucky Looter, Ninja Movement, Shadows, Hidden Strike)
Or the Joe's female dog build (Lucky Looter, Rule 1, Better Barter, Daring Adventurer)
Or the Naturalist build (Motherlode, Miner 69'er, Huntsman, Living o/t Land)
Or even the freaking Hobo build (Slow Metabolism, Well Hydrated, Immunity, Well Insulated)
That's right. With only 11 points, which you can have by level 6!, you can be a burgeoning hobo that is resistant to all the natural ways of dying by starvation, dehydration, food poisoning, dysentery, infection, pneumonia, and even ambient temperature.