I have this bug as well currently in my MP world. I think it has something to do with the sheer number of things I have about. I have a massive tradeskill/home base with a tree farm and a huge garden (this is to serve 5 people) along with a severe number of storage boxes, and a thorough garage door and security system with automated turrets. The boxes appear and disappear constantly, even though I may still interact with them and use them properly. It's frustrating but I never have this issue with any of the smaller outposts I put in other more remote portions of the map.
Yeah just a lot of crap everywhere. I tested the amount of assets you can have in your current chunk and it falls flat after a while.
What I did was to plant a corn field that is 20x20 and keep expanding out and you'll see what I mean. After a while there's a critical number of items
that causes stuttering, bugs, andd may even potentially crash your game.